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This chapter discusses the adverse effects of antihelminthic drugs on the physiology of the human, such as albendazole, mebendazole, diethylcarbamazine, ivermectin, and levamisole. This product contains 10 mg moxidectin/ml (or 1%) so it's much more economical to use at the rate of 2.5 ccs per 100 lbs of goat. ... DO NOT allow material to contact humans, exposed food or food utensils. It is used for parasite control in horses in an oral gel formulation. This effect may be more pronounced in … Barber's pole worm (Haemonchus contortus) is a potentially harmful roundworm parasite of sheep which can cause a disease called haemonchosis. Administer 1 mL per 11 lb (1 mL per 5 kg) body weight into the mouth of the sheep, ... HUMAN WARNINGS: Not for use in humans. To obtain a copy of the material safety data sheet (MSDS) which provides more detailed occupational safety information or to report adverse reactions attributable to exposure to this product, call 1-800-422-9874. Cydectin Pour-On is available in five convenient container sizes. 4.6 out of 5 stars 14. … Moxidectin is a second generation macrocyclic lactone (ML) with potent endectocide activity. Data sources include IBM Watson Micromedex (updated 2 Nov 2020), Cerner Multum™ (updated 2 Nov 2020), ASHP (updated 23 Oct 2020) and others. If animals are likely to be reinfected following treatment, a strategic parasite control program should be established. For external use only. Do not contaminate water by direct application or by improper disposal of drug containers. CYDECTIN Long Acting Injection for Sheep Lambs/hoggets born in the previous spring are widely recognised as the highest risk group of sheep on New Zealand farms likely to suffer from worm effects. HUMAN WARNINGS: Not for use in humans. Attach the applicator feeder hose to the vented cap. Meat and milk from cattle treated with CYDECTIN (moxidectin) Pour-On may be used for human consumption at any time following treatment. Cydectin Oral Drench for Sheep has been formulated specifically for oral use in sheep and should not be given by any other route of administration. Is ivermectin safe? Leptospirosis notifications and laboratory-reported cases by year, 1997 - 2013. Cydectin LA Oral Drench for Sheep is a ready-to-use solution containing 0.1% Cydectin LA. This product has been formulated specifically for topical use in cattle and should not be used in other animal species or by other routes of administration as adverse reactions may occur. Eight subjects had dizziness or somnolence/lethargy (one in the placebo group, two who took 9 mg, one who took 18 mg, and four who took 36 mg). In case of accidental skin contact and/or clothing contamination, wash skin thoroughly with … Do not apply to areas of skin with mange scabs, skin lesions, mud or manure. It is thought to work by paralysing the parasite or inactivating the parasite gut. (16.91 fl oz/500 mL and 33.81 fl oz/1 L Bottles). Holding the dosing chamber as shown below, pour this measured volume of solution evenly along the backline of the animal from the withers to the tailhead (see Figure 1). It would be like a human trying to live on Mars. bovis). A protective barrier, called the blood-brain barrier, blocks ivermectin from reaching the human brain. Sites for administration of CYDECTIN Injectable. Specific target organ toxicity, single exposure Category 3 narcotic effects Hazardous to the aquatic environment, acute Category 2 hazard ... For animal injection only. Moxidectin, also known as ProHeart®, is used primarily to prevent heartworm infection for dogs. Squeeze-Measure-Pour System 16.91 fl oz/500 mL and 33.81 fl oz/1 L Bottles), Large Conventional Containers (84.54 fl oz/2.5 L and 169 fl oz/5 LBottles and 338 fl oz/10 L Cubetainer). Side effects are uncommon but may include lethargy, vomiting, uncoordinated walking, anorexia, diarrhea, and itching. Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. In case of accidental skin contact and/or clothing contamination, wash skin thoroughly with soap and water and launder clothing with detergent. Not for use in humans. Figure 3. This is a disease that is easily spread from animal to humans and is the world’s most widespread zoonosis. To obtain a copy of the material safety data sheet (MSDS) which provides more detailed occupational safety information or to report adverse reactions attributable to exposure to this product, call 1-866-638-2226. When used according to label directions, neither a pre-slaughter drug withdrawal period nor a milk discard time are required. 4,916,154 - used under license. For the treatment and control of infections caused by moxidectin sensitive strains of the following endoparasites and ectoparasites: Gastro-intestinal nematodes (stomach & gut worms), respiratory tract nematode (lung worm) and Psoroptes ovis (scab mite). Cydectin LA acts by interfering with chloride channel-mediated neurotransmission in the parasite. Directions for use of each container type follow: Squeeze-Measure-Pour System Side-effects Lethargy Vomiting Diarrhea Loss of appetite Stumbling Cydectin Solution may also cause side-effects not listed here. CYDECTIN Oral Drench for Sheep, when administered at the recommended dose level of 0.2 mg moxidectin/2.2 lb (0.2 mg/kg) body weight, is effective in the treatment and control of adult and larval (L 4) stages of the following internal parasites of sheep: Parasites. The information is written by veterinary experts, peer-reviewed and presented in a practical format with a high visual clinical content to improve disease awareness and highlight disease prevention. Dosage Form: FOR ANIMAL USE ONLY, For Treatment of Infections and Infestations Due to Internal and External Parasites of Beef and Dairy Cattle. For the prevention and treatment of psoroptic mange (scab) in sheep. To obtain a copy of the material safety data sheet (MSDS) which provides more detailed occupational safety information or to report adverse reactions attributable to exposure to this product, call 1-866-638-2226. In horses, overdose may lead to depression , drooping of the lower lip, tremor , lack of coordination when moving ( ataxia ), decreased rate of breathing ( respiratory rate ), stupor and coma . P.J.J. The table below will assist in the calculation of the appropriate volume of pour-on which must be applied based on the weight of animal being treated. The table below will assist in the calculation of the appropriate volume of drench in 1.0 mL increments and it must be administered based on the weight of animal being treated. Apply the recommended volume of Cydectin Pour-On evenly along the backline of the animal from the withers to the tailhead (see Figure 1). (16.91 fl oz/500 mL and 33.81 fl oz/1 L Bottles), Large Conventional Containers (84.54 fl oz/2.5 L and 169 fl oz/5 L. Not For Use In Humans. CYDECTIN is a member of the avermectin/milbemycin 3-ML class of anthelmintics. In case of human injection, consult a doctor immediately and apply ice or cold pack to injection site while avoiding direct contact with the skin. Phone: (02)9899 0444 Page 2 of 4 Issued: 4 Jul 2002 Revision 5 ll HEALTH HAZARD DATA Health Effects: No specific data is available for the product for chronic exposure symptoms. Though off label Cydectin Pouron is an accepted and widely used med for poultry and caged birds. The persistent activity of CYDECTIN POUR-ON FOR CATTLE & RED DEER prevents the development of viable cattle tick (Rhipicephalus (Boophilus) microplus) for 21 days after treatment. For Treatment and Control of Infections Due to Internal Parasites of Sheep. No toxic signs were seen in cattle given up to 25 times the recommended dose level. Moxidectin acts by interfering with chloride channel-mediated neurotransmission in the parasite. Cattle entering the herd following this administration should be treated prior to introduction. Keep this and all drugs out of the reach of children. Cydectin Pour-On is effective against the migrating stage of cattle grubs (Hypoderma larvae). So it appears, with a real minimum of information, that a human effective dose would be between 0.15 and 0.6 mg per kg or approximately 0.1 to 0.3 mg per pound. Cattle treated with Cydectin Pour-On at the end of fly season can be re-treated during the winter without danger of grub-related reactions. HUMAN WARNINGS: Not for use in humans. Dosage Form: FOR ANIMAL USE ONLY. ; RECOMMENDED FOR. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. St. Joseph, MO 64506 U.S.A. Cydectin Oral Drench for Sheep is a ready-to-use solution containing 0.1% moxidectin. Reproductive safety studies evaluating the use of Cydectin Oral Drench in breeding ewes and rams have not been conducted in the U.S. Store product at or below 77°F (25°C). Moxidectin is an endectocide in the milbemycin chemical class which shares the distinctive mode of action characteristic of macrocyclic lactones. © 2010 Boehringer Ingelheim Vetmedica, Inc. All Rights Reserved. Due to the angular topline characteristic of most dairy breeds, it is recommended that all pour-on products be applied slowly to dairy cows. If you have any questions, please contact your veterinarian. Components Species Test Results Ethanol (CAS 64-17-5) LC50 Cat Inhalation Acute 85.41 mg/l, 4.5 Hours Cydectin® Injectable SDS US 921783 Version #: 01 Revision date: - Issue date: 05-September-2014 4 / 8 Free moxidectin may adversely affect fish and certain aquatic organisms. The recommended rate of administration for Cydectin 1% Oral Drench for Sheep is 1 mL per 11 lb (5 kg) body weight to provide 0.2 mg moxidectin/2.2 lb (0.2 mg/kg) body weight. I use Ivomec injectable, given orally, 1ml per 50lbs. Not for use in humans. Not For Use in Humans. Keep this and all drugs out of the reach of children. CYDECTIN (moxidectin) Pour-On is specially formulated to allow moxidectin to be absorbed through the skin and distributed internally to the areas of the body affected by endo- and/or ectoparasitism. For customer service or to obtain product information, including Safety Data Sheet (SDS), call 1-800-633-3796. The recommended rate of administration for Cydectin Oral Drench for Sheep is 1 mL per 11 lb (5 kg) body weight to provide 0.2 mg moxidectin/2.2 lb (0.2 mg/kg) body weight. Figure 2. Cydectin Triclamox Pour On is for the treatment of mixed trematode (fluke) and nematode (roundworm) infections and certain arthropod infestations. For customer service or to obtain product information, including Safety Data Sheet (SDS), call 1-800-633-3796. Moxidectin is an endectocide in the milbemycin chemical class which shares the distinctive mode of action characteristic of macrocyclic lactones. Can develop very rapidly and cause Sheep deaths without warning have demonstrated an margin. Species as severe adverse reactions, including death accidental skin contact and/or clothing contamination, wash skin thoroughly with and... The effect of gamma-aminobutyric acid in the vertebral canal may cause bloat contortus ( barber’s pole worm Haemonchus... 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